Motif ID: FOX{F1,F2,J1}.p2

Z-value: 1.813


Transcription factors associated with FOX{F1,F2,J1}.p2:

Gene SymbolEntrez IDGene Name
FOXF1 2294 forkhead box F1
FOXF2 2295 forkhead box F2
FOXJ1 2302 forkhead box J1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXJ1chr17_-_716489650.665.3e-03Click!
FOXF1chr16_+_85101605-0.322.3e-01Click!
FOXF2chr6_+_1335067-0.302.6e-01Click!


Activity profile for motif FOX{F1,F2,J1}.p2.

activity profile for motif FOX{F1,F2,J1}.p2


Sorted Z-values histogram for motif FOX{F1,F2,J1}.p2

Sorted Z-values for motif FOX{F1,F2,J1}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{F1,F2,J1}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_159459814 8.735 APOA2
apolipoprotein A-II
chr1_-_159459999 8.268 NM_001643
APOA2
apolipoprotein A-II
chr4_+_74488910 5.237 ALB
albumin
chr22_+_19458378 4.975 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr4_+_74488835 4.947 NM_000477
ALB
albumin
chr7_+_134483305 4.755 NM_018295
TMEM140
transmembrane protein 140
chr4_+_100714995 4.097 MTTP
microsomal triglyceride transfer protein
chr17_-_7023283 4.059 ASGR1
asialoglycoprotein receptor 1
chr17_-_7023378 3.336 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr1_-_167822248 3.323 F5
coagulation factor V (proaccelerin, labile factor)
chr12_-_101835026 3.243 PAH
phenylalanine hydroxylase
chr14_-_93859394 3.232 NM_001756
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr17_+_69939130 2.985 NM_022036
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr1_-_167822334 2.911 NM_000130
F5
coagulation factor V (proaccelerin, labile factor)
chr6_-_41823056 2.859 NM_001166424
NM_002630
PGC

progastricsin (pepsinogen C)

chrX_-_131401319 2.844 NM_018388
NM_133486
MBNL3

muscleblind-like 3 (Drosophila)

chr10_-_52315390 2.764 A1CF
APOBEC1 complementation factor
chr9_-_115880494 2.722 NM_001633
AMBP
alpha-1-microglobulin/bikunin precursor
chr9_-_115880366 2.706 AMBP
alpha-1-microglobulin/bikunin precursor
chr2_+_33514896 2.705 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr14_+_94148466 2.701 NM_001085
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr13_-_45654296 2.549 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr13_-_45654327 2.528 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr12_-_61615124 2.463 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr9_-_115880281 2.440 AMBP
alpha-1-microglobulin/bikunin precursor
chr10_-_69267774 2.436 NM_021800
NM_201262
DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr17_-_23721468 2.435 VTN
vitronectin
chr4_+_155703581 2.427 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr10_-_52315436 2.378 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr17_-_23721430 2.377 VTN
vitronectin
chr13_-_40138607 2.332 NM_002015
FOXO1
forkhead box O1
chr17_-_23721420 2.313 VTN
vitronectin
chr19_-_53081326 2.282 SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr20_-_45410033 2.236 ZMYND8
zinc finger, MYND-type containing 8
chr1_+_190811479 2.220 NM_002922
RGS1
regulator of G-protein signaling 1
chr19_+_18357966 2.172 NM_004864
GDF15
growth differentiation factor 15
chr4_+_68107039 2.084 NM_012108
STAP1
signal transducing adaptor family member 1
chr12_-_69837831 2.075 TSPAN8
tetraspanin 8
chr3_-_12561962 2.075 NM_001195279
LOC100129480
hypothetical protein LOC100129480
chr6_+_32003180 2.036 NM_000063
NM_001145903
C2

complement component 2

chr9_-_115880372 2.007 AMBP
alpha-1-microglobulin/bikunin precursor
chr6_+_12825818 1.981 NM_030948
PHACTR1
phosphatase and actin regulator 1
chr17_-_23721351 1.969 VTN
vitronectin
chr4_+_71096830 1.954 NM_017855
ODAM
odontogenic, ameloblast asssociated
chr1_-_24342158 1.936 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chr10_+_102722275 1.917 NM_017893
SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr6_+_64403668 1.905 PHF3
PHD finger protein 3
chr20_-_22514092 1.880 NM_153675
FOXA2
forkhead box A2
chr1_+_225194582 1.877 ADCK3
aarF domain containing kinase 3
chr1_-_92124201 1.865 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr11_-_114880275 1.862 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr4_+_74498042 1.860 ALB
albumin
chr1_+_225194616 1.820 ADCK3
aarF domain containing kinase 3
chr2_+_86800898 1.785 NM_022780
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr12_-_94914133 1.765 NM_002108
HAL
histidine ammonia-lyase
chr17_-_26665213 1.750 EVI2B
ecotropic viral integration site 2B
chr17_+_64922420 1.727 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr4_+_69716298 1.720 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr11_-_116213511 1.707 NM_000039
APOA1
apolipoprotein A-I
chr13_-_45654292 1.697 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_-_24067347 1.697 NM_000147
FUCA1
fucosidase, alpha-L- 1, tissue
chr8_-_81155564 1.693 NM_001025252
TPD52
tumor protein D52
chr2_+_74913289 1.689 NM_000189
HK2
hexokinase 2
chr17_-_26665144 1.669 EVI2B
ecotropic viral integration site 2B
chr4_-_155731288 1.661 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr12_-_51629874 1.659 KRT8
keratin 8
chr3_+_99934227 1.639 NM_006100
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr2_+_11591692 1.631 NM_014668
GREB1
growth regulation by estrogen in breast cancer 1
chr1_+_225194622 1.607 ADCK3
aarF domain containing kinase 3
chr2_+_86800940 1.590 RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr10_+_7785347 1.589 ITIH2
inter-alpha (globulin) inhibitor H2
chr4_+_74488947 1.586 ALB
albumin
chr8_-_28299508 1.583 ZNF395
zinc finger protein 395
chr2_-_165133239 1.581 GRB14
growth factor receptor-bound protein 14
chr2_+_219354692 1.570 NM_000784
CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
chr7_-_87180499 1.557 NM_000927
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr10_+_7785331 1.520 ITIH2
inter-alpha (globulin) inhibitor H2
chr8_-_28299850 1.515 NM_018660
ZNF395
zinc finger protein 395
chr17_-_26665220 1.512 NM_006495
EVI2B
ecotropic viral integration site 2B
chr17_-_26665194 1.500 EVI2B
ecotropic viral integration site 2B
chr6_-_26038817 1.490 NM_005835
SLC17A2
solute carrier family 17 (sodium phosphate), member 2
chr9_-_115880425 1.444 AMBP
alpha-1-microglobulin/bikunin precursor
chr5_-_98290117 1.380 NM_001270
CHD1
chromodomain helicase DNA binding protein 1
chr2_+_88966170 1.377


chr2_+_143351695 1.365 KYNU
kynureninase
chr4_+_38740246 1.359 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr2_-_43919392 1.357 NM_022436
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr2_-_121875610 1.350 CLASP1
cytoplasmic linker associated protein 1
chr12_+_6473519 1.341 NCAPD2
non-SMC condensin I complex, subunit D2
chr15_+_72694387 1.334 NM_001130028
CLK3
CDC-like kinase 3
chr9_+_79158164 1.306 VPS13A
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr2_+_86801081 1.298 RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr12_-_31370305 1.282 FAM60A
family with sequence similarity 60, member A
chr20_-_62052922 1.277 NM_001193379
UCKL1
uridine-cytidine kinase 1-like 1
chr10_+_4995597 1.267 AKR1C1
AKR1C3
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr3_+_142175329 1.260 SLC25A36
solute carrier family 25, member 36
chr4_+_74491272 1.232 ALB
albumin
chr3_-_184756101 1.232 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr1_-_92124064 1.231 TGFBR3
transforming growth factor, beta receptor III
chr7_+_133884388 1.219 NM_001080538
AKR1B15
aldo-keto reductase family 1, member B15
chr1_+_111483771 1.218 NM_001007794
CEPT1
choline/ethanolamine phosphotransferase 1
chr1_+_225194560 1.203 NM_020247
ADCK3
aarF domain containing kinase 3
chr10_+_4995453 1.183 NM_001353
AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr14_+_99633570 1.182 EVL
Enah/Vasp-like
chr10_+_7785290 1.167 ITIH2
inter-alpha (globulin) inhibitor H2
chr17_-_6958695 1.161 ASGR2
asialoglycoprotein receptor 2
chr10_+_7785360 1.158 ITIH2
inter-alpha (globulin) inhibitor H2
chr2_+_143351536 1.156 NM_001032998
NM_003937
KYNU

kynureninase

chr11_+_22644732 1.148 NM_001143830
GAS2
growth arrest-specific 2
chr12_-_31370351 1.139 FAM60A
family with sequence similarity 60, member A
chr1_-_57204208 1.126 NM_000066
C8B
complement component 8, beta polypeptide
chr14_-_20562962 1.122 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr15_-_68781662 1.122 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr12_-_9159789 1.119 NM_000014
A2M
alpha-2-macroglobulin
chr20_-_44426407 1.111 NM_015945
NM_173073
NM_173179
SLC35C2


solute carrier family 35, member C2


chr10_-_5035967 1.094 NM_001135241
AKR1C1
AKR1C2
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr7_-_140270749 1.081 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr2_+_219751192 1.080 FAM134A
family with sequence similarity 134, member A
chr7_-_25234582 1.074 NM_022150
NPVF
neuropeptide VF precursor
chr12_-_31370387 1.071 NM_001135811
NM_021238
NM_001135812
FAM60A


family with sequence similarity 60, member A


chr10_-_44794146 1.063 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr7_+_1094248 1.063 NM_001098201
GPER
G protein-coupled estrogen receptor 1
chr11_-_64906683 1.040 NM_001077241
NM_182556
SLC25A45

solute carrier family 25, member 45

chr12_-_69838045 1.016 NM_004616
TSPAN8
tetraspanin 8
chr17_-_23721485 0.990 NM_000638
VTN
vitronectin
chr1_-_228916958 0.975 NM_000029
AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr10_+_7785235 0.970 NM_002216
ITIH2
inter-alpha (globulin) inhibitor H2
chr16_-_29797172 0.963 SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr2_+_176761552 0.953 NM_024501
HOXD1
homeobox D1
chr21_+_33524174 0.952 IFNAR2
interferon (alpha, beta and omega) receptor 2
chr22_+_35639564 0.938 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr2_-_88707978 0.934 NM_004836
EIF2AK3
eukaryotic translation initiation factor 2-alpha kinase 3
chr14_-_73620912 0.928 NM_005589
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr14_-_73620826 0.921 ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chrX_-_15198093 0.918 NM_001031739
NM_001168530
NM_024087
ASB9


ankyrin repeat and SOCS box containing 9


chr16_+_75790849 0.914 NM_001129979
SYCE1L
synaptonemal complex central element protein 1-like
chr14_-_19867372 0.907 NM_182852
NM_182851
CCNB1IP1

cyclin B1 interacting protein 1, E3 ubiquitin protein ligase

chr10_+_4995685 0.898 AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr1_+_205344200 0.894 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr13_-_98708549 0.884 NM_001098200
NM_005292
GPR18

G protein-coupled receptor 18

chrX_-_48578878 0.883 NM_013271
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr14_+_20226762 0.883 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr19_-_38052481 0.875 NM_001126335
NM_014270
SLC7A9

solute carrier family 7 (cationic amino acid transporter, y+ system), member 9

chr14_-_99140195 0.873 NM_001144995
CCDC85C
coiled-coil domain containing 85C
chr18_-_50777634 0.872 NM_025214
CCDC68
coiled-coil domain containing 68
chr6_+_114285209 0.855 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr10_+_5126589 0.836 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr1_+_196874867 0.831 PTPRC
protein tyrosine phosphatase, receptor type, C
chrX_+_46825179 0.829 RGN
regucalcin (senescence marker protein-30)
chr2_-_128332143 0.824 POLR2D
polymerase (RNA) II (DNA directed) polypeptide D
chr6_-_76259976 0.813 NM_015687
FILIP1
filamin A interacting protein 1
chr21_+_33524075 0.809 NM_000874
NM_207584
NM_207585
IFNAR2


interferon (alpha, beta and omega) receptor 2


chr5_+_70980724 0.800 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr6_+_30238961 0.793 NM_033229
TRIM15
tripartite motif containing 15
chr2_-_128332161 0.783 POLR2D
polymerase (RNA) II (DNA directed) polypeptide D
chr14_+_87541220 0.772 NM_003608
GPR65
G protein-coupled receptor 65
chr1_+_32512298 0.769 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr1_-_245120900 0.769 AHCTF1
AT hook containing transcription factor 1
chr10_-_54201400 0.768 NM_000242
MBL2
mannose-binding lectin (protein C) 2, soluble
chr5_-_131160541 0.765 FNIP1
folliculin interacting protein 1
chr5_-_42847716 0.761 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chrX_-_74292800 0.759 NM_004299
ABCB7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr11_-_46572073 0.754 AMBRA1
autophagy/beclin-1 regulator 1
chr1_-_229627412 0.753 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr1_+_50344550 0.736 NM_001144775
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr12_-_9804682 0.719 NM_001781
CD69
CD69 molecule
chr4_-_151990061 0.715 LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr13_+_40783340 0.712 NM_001110798
NM_024561
NM_018527
NAA16


N(alpha)-acetyltransferase 16, NatA auxiliary subunit


chr6_-_43135092 0.711 NM_015950
MRPL2
mitochondrial ribosomal protein L2
chr18_+_58533597 0.707 NM_194449
PHLPP1
PH domain and leucine rich repeat protein phosphatase 1
chr2_+_99344060 0.702 EIF5B
eukaryotic translation initiation factor 5B
chr3_-_58497913 0.701 NM_003500
ACOX2
acyl-CoA oxidase 2, branched chain
chr14_+_101346032 0.700 PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr7_+_73262022 0.690 NM_014146
NM_032463
NM_032464
LAT2


linker for activation of T cells family, member 2


chr21_+_33524124 0.684 IFNAR2
interferon (alpha, beta and omega) receptor 2
chr10_+_5126613 0.682 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr6_-_150099352 0.680 NUP43
nucleoporin 43kDa
chrX_+_70232362 0.680 NM_001170931
NM_005938
FOXO4

forkhead box O4

chr17_-_6958773 0.675 NM_001181
NM_080912
NM_080913
ASGR2


asialoglycoprotein receptor 2


chr1_+_158975662 0.670 NM_021181
SLAMF7
SLAM family member 7
chr4_+_74520796 0.669 NM_001134
AFP
alpha-fetoprotein
chr1_-_149681265 0.663 NM_207171
POGZ
pogo transposable element with ZNF domain
chr7_+_119700924 0.660 NM_012281
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr8_+_67096344 0.654 NM_033105
DNAJC5B
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr16_-_11282595 0.652 NM_002761
PRM1
protamine 1
chr19_-_44518516 0.652 NM_004877
GMFG
glia maturation factor, gamma
chr2_+_143603439 0.652 ARHGAP15
Rho GTPase activating protein 15
chr7_-_139123906 0.647 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chr1_-_205161821 0.647 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr8_-_134378630 0.645 NM_001135242
NM_006096
NDRG1

N-myc downstream regulated 1

chr4_+_187424111 0.645 NM_000128
F11
coagulation factor XI
chr12_-_101115677 0.642 NM_002674
PMCH
pro-melanin-concentrating hormone
chr12_-_101835510 0.642 NM_000277
PAH
phenylalanine hydroxylase
chr7_+_111850367 0.642 NM_001007245
NM_001197080
IFRD1

interferon-related developmental regulator 1

chr16_+_80370426 0.638 NM_002661
PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr6_-_32892705 0.635 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr5_-_169657395 0.624 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr7_+_44612705 0.618 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr13_-_47885653 0.618 NM_001162498
LPAR6
lysophosphatidic acid receptor 6
chr12_-_47790604 0.615 LMBR1L
limb region 1 homolog (mouse)-like

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
5.47 5.22e-03 GO:0008206 bile acid metabolic process

Nothing significant found in compartment category.

Nothing significant found in function category.